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ACTN2 抗体

The 小鼠 单克隆 anti-ACTN2 antibody (Clone GT1253) (ABIN7466141) specifically detects ACTN2 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7466141
发货至: 中国
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Quick Overview for ACTN2 抗体 (ABIN7466141)

抗原

See all ACTN2 抗体
ACTN2 (Actinin, alpha 2 (ACTN2))

适用

  • 104
  • 79
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宿主

  • 97
  • 37
小鼠

克隆类型

  • 68
  • 66
单克隆

标记

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  • 1
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This ACTN2 antibody is un-conjugated

应用范围

  • 104
  • 72
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  • 4
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

GT1253
  • 特异性

    Based on sequence homology, this antibody may cross react with ACTN1 protein.

    交叉反应

    人, 小鼠

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human alpha Actinin 2. The exact sequence is proprietary.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.27 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ACTN2 (Actinin, alpha 2 (ACTN2))

    别名

    actinin alpha 2

    背景

    Actinin alpha 2 , CMD1AA , CMH23,Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq]

    分子量

    104 kDa

    基因ID

    88

    UniProt

    P35609

    途径

    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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