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Adenylosuccinate Lyase 抗体

This 兔 多克隆 anti-Adenylosuccinate Lyase antibody specifically detects Adenylosuccinate Lyase in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7466064
发货至: 中国
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Quick Overview for Adenylosuccinate Lyase 抗体 (ABIN7466064)

抗原

See all Adenylosuccinate Lyase (ADSL) 抗体
Adenylosuccinate Lyase (ADSL)

适用

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宿主

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克隆类型

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多克隆

标记

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This Adenylosuccinate Lyase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human ADSL. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.34 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Adenylosuccinate Lyase (ADSL)

    别名

    adenylosuccinate lyase

    背景

    Adenylosuccinate lyase , AMPS , ASASE , ASL,Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    分子量

    55 kDa

    基因ID

    158

    UniProt

    P30566

    途径

    Ribonucleoside Biosynthetic Process
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