SAFB 抗体 (AA 345-357)
Quick Overview for SAFB 抗体 (AA 345-357) (ABIN7466004)
抗原
See all SAFB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 345-357
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交叉反应
- 人, 小鼠
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纯化方法
- Protein G purified
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免疫原
- A synthetic peptide corresponding to amino acids 345-357 (PEARDSKEDGRKF) of the human SAFB protein.
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亚型
- IgG1
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应用备注
- WB: 1 - 2 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa, MCF7
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SAFB (Scaffold Attachment Factor B (SAFB))
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别名
- scaffold attachment factor B
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背景
- Scaffold attachment factor B , HAP , HET , SAB-B1 , SAF-B , SAF-B1 , SAFB1,This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
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分子量
- 103 kDa
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基因ID
- 6294
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UniProt
- Q15424
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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