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SAFB 抗体 (AA 345-357)

This anti-SAFB antibody is a 小鼠 单克隆 antibody detecting SAFB in WB, IHC, IF, IP 和 ICC. Suitable for 人.
产品编号 ABIN7466004
发货至: 中国

Quick Overview for SAFB 抗体 (AA 345-357) (ABIN7466004)

抗原

See all SAFB 抗体
SAFB (Scaffold Attachment Factor B (SAFB))

适用

  • 36
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宿主

  • 41
  • 10
小鼠

克隆类型

  • 39
  • 12
单克隆

标记

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  • 1
  • 1
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This SAFB antibody is un-conjugated

应用范围

  • 34
  • 16
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  • 12
  • 9
  • 8
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  • 3
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  • 2
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

6F7
  • 抗原表位

    • 15
    • 8
    • 5
    • 5
    • 2
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    • 1
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    AA 345-357

    交叉反应

    人, 小鼠

    纯化方法

    Protein G purified

    免疫原

    A synthetic peptide corresponding to amino acids 345-357 (PEARDSKEDGRKF) of the human SAFB protein.

    亚型

    IgG1
  • 应用备注

    WB: 1 - 2 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HeLa, MCF7

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    SAFB (Scaffold Attachment Factor B (SAFB))

    别名

    scaffold attachment factor B

    背景

    Scaffold attachment factor B , HAP , HET , SAB-B1 , SAF-B , SAF-B1 , SAFB1,This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]

    分子量

    103 kDa

    基因ID

    6294

    UniProt

    Q15424

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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