ITM2C 抗体
This anti-ITM2C antibody is a 兔 多克隆 antibody detecting ITM2C in WB, IHC (p) 和 FACS. Suitable for 人.
Quick Overview for ITM2C 抗体 (ABIN7465877)
抗原
See all ITM2C 抗体
ITM2C
(Integral Membrane Protein 2C (ITM2C))
适用
人
宿主
兔
克隆类型
多克隆
标记
This ITM2C antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
-
-
交叉反应
- 人
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human ITM2C. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Integral Membrane Protein 2C (ITM2C) (AA 1-230) antibody
ITM2C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 101-150) antibodyITM2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: HeLa
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.7 mg/mL
-
缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- ITM2C (Integral Membrane Protein 2C (ITM2C))
-
别名
- integral membrane protein 2C
-
背景
- Integral membrane protein 2C , BRI3 , BRICD2C , E25 , E25C , ITM3,Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
-
分子量
- 30 kDa
-
基因ID
- 81618
-
UniProt
- Q9NQX7
抗原
-
You are here:
