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PATZ1 抗体 (N-Term)

This anti-PATZ1 antibody is a 兔 多克隆 antibody detecting PATZ1 in WB, IF, IHC (p) 和 ICC. Suitable for 人.
产品编号 ABIN7465764
发货至: 中国

Quick Overview for PATZ1 抗体 (N-Term) (ABIN7465764)

抗原

See all PATZ1 (ZNF278) 抗体
PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))

适用

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宿主

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克隆类型

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多克隆

标记

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This PATZ1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
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    N-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human PATZ1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HCT116

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.72 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))

    别名

    POZ/BTB and AT hook containing zinc finger 1

    背景

    POZ/BTB and AT hook containing zinc finger 1 , MAZR , PATZ , RIAZ , ZBTB19 , ZNF278 , ZSG , dJ400N23,The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1,22)(p36.1,q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq]

    分子量

    74 kDa

    基因ID

    23598

    UniProt

    Q9HBE1
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