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CARD11 抗体 (N-Term)

This 兔 多克隆 anti-CARD11 antibody specifically detects CARD11 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7465644
发货至: 中国
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Quick Overview for CARD11 抗体 (N-Term) (ABIN7465644)

抗原

See all CARD11 抗体
CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

适用

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宿主

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克隆类型

  • 33
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多克隆

标记

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This CARD11 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human CARD11. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: BCL-1 , Raji , K562 , NCI-H929

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.02 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

    别名

    caspase recruitment domain family member 11

    背景

    Caspase recruitment domain family member 11 , BENTA , BIMP3 , CARMA1 , IMD11 , IMD11A , PPBL,The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq]

    分子量

    133 kDa

    基因ID

    84433

    UniProt

    Q9BXL7

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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