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UNC13D 抗体 (N-Term)

This anti-UNC13D antibody is a 兔 多克隆 antibody detecting UNC13D in WB. Suitable for 人.
产品编号 ABIN7465484
发货至: 中国
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Quick Overview for UNC13D 抗体 (N-Term) (ABIN7465484)

抗原

See all UNC13D 抗体
UNC13D (Unc-13 Homolog D (UNC13D))

适用

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宿主

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克隆类型

  • 24
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多克隆

标记

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This UNC13D antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human Munc 13-4. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431 , Mouse lung

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    UNC13D (Unc-13 Homolog D (UNC13D))

    别名

    unc-13 homolog D

    背景

    Unc-13 homolog D , FHL3 , HLH3 , HPLH3 , Munc13-4,This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq]

    分子量

    123 kDa

    基因ID

    201294

    UniProt

    Q70J99

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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