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Aconitase 1 抗体

The 兔 多克隆 anti-Aconitase 1 antibody is suitable to detect Aconitase 1 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7465450
发货至: 中国
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Quick Overview for Aconitase 1 抗体 (ABIN7465450)

抗原

See all Aconitase 1 (ACO1) 抗体
Aconitase 1 (ACO1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Aconitase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Aconitase 1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431 , HeLa , HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Aconitase 1 (ACO1)

    别名

    aconitase 1

    背景

    Aconitase 1 , ACONS , HEL60 , IREB1 , IREBP , IREBP1 , IRP1,Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq]

    分子量

    98 kDa

    基因ID

    48

    UniProt

    P21399

    途径

    Transition Metal Ion Homeostasis
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