EIF3H 抗体
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北京 101111
Quick Overview for EIF3H 抗体 (ABIN7465416)
抗原
See all EIF3H 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠
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纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human eIF3H / EIF3S3. The exact sequence is proprietary.
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亚型
- IgG2b
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anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) (AA 80-340) antibody
EIF3H 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) (AA 234-263), (C-Term) antibodyEIF3H 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20154 unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) antibodyEIF3H 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) (AA 152-250) antibodyEIF3H 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) (N-Term) antibodyEIF3H 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) (AA 80-340) antibodyEIF3H 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) antibodyEIF3H 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) (N-Term) antibodyEIF3H 适用: 人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) (AA 246-295) antibodyEIF3H 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, 非洲爪蟾, Pig, 小鸡, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H) (C-Term) antibodyEIF3H 适用: 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾, 斑马鱼, 小鸡, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
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别名
- eukaryotic translation initiation factor 3 subunit H
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背景
- Eukaryotic translation initiation factor 3 subunit H , EIF3S3 , eIF3-gamma , eIF3-p40,Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
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分子量
- 40 kDa
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基因ID
- 8667
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UniProt
- O15372
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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