EIF3H 抗体
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- 抗原 See all EIF3H 抗体
- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This EIF3H antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Affinity purified by Protein G.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human eIF3H / EIF3S3. The exact sequence is proprietary.
- 克隆位点
- GT2712
- 亚型
- IgG1
- Top Product
- Discover our top product EIF3H Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: A431
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, No Preservative
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
- 别名
- eukaryotic translation initiation factor 3 subunit H (EIF3H 产品)
- 别名
- EIF3S3 antibody, eIF3-gamma antibody, eIF3-p40 antibody, 1110008A16Rik antibody, 40kD antibody, 9430017H16Rik antibody, EIF3-P40 antibody, EIF3-gamma antibody, Eif3s3 antibody, eif3s3 antibody, eIF-3p40 antibody, En10 antibody, AO090038000435 antibody, EIF3H antibody, eIF3h antibody, BcDNA:GM14618 antibody, CG9124 antibody, Dmel\\CG9124 antibody, eIF-3 antibody, eIF3-S3 antibody, eIf3-p44 antibody, l(2)k09003 antibody, eIF3h-A antibody, eif3h antibody, fj02c04 antibody, wu:fj02c04 antibody, zgc:101085 antibody, eIF3h-B antibody, zgc:123049 antibody, eukaryotic translation initiation factor 3 subunit H antibody, eukaryotic translation initiation factor 3, subunit H antibody, eukaryotic translation initiation factor 3 subunit H S homeolog antibody, eukaryotic translation initiation factor 3 subunit H-like antibody, Eukaryotic initiation factor 3 p40 subunit antibody, eukaryotic translation initiation factor 3, subunit H, a antibody, Eukaryotic translation initiation factor 3 subunit H antibody, translation initiation factor eIF3h (p40) antibody, eukaryotic translation initiation factor 3, subunit H, b antibody, EIF3H antibody, Eif3h antibody, eif3h antibody, eif3h.S antibody, eIF3h antibody, AOR_1_722074 antibody, PAAG_02837 antibody, VDBG_01433 antibody, MGYG_06658 antibody, LOC100196680 antibody, eIF-3p40 antibody, eif3ha antibody, eif-3.H antibody, SPAC821.05 antibody, eif3hb antibody
- 背景
- Eukaryotic translation initiation factor 3 subunit H , EIF3S3 , eIF3-gamma , eIF3-p40,Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
- 分子量
- 40 kDa
- 基因ID
- 8667
- UniProt
- O15372
- 途径
- Ribonucleoprotein Complex Subunit Organization
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