USP20 抗体
Quick Overview for USP20 抗体 (ABIN7465301)
抗原
See all USP20 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human USP20. The exact sequence is proprietary.
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibody
USP20 适用: 人, 犬, 兔, 马, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 适用: 人, 犬, 兔, 马, 小鸡, Cow, Pig, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (C-Term) antibodyVerified USP20 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 361-410) antibodyUSP20 适用: 人, 大鼠, 兔, 小鸡, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 814-844), (C-Term) antibodyUSP20 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4351 unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , Raji
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.98 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
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别名
- ubiquitin specific peptidase 20
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背景
- Ubiquitin specific peptidase 20 , LSFR3A , VDU2 , hVDU2,Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
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分子量
- 102 kDa
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基因ID
- 10868
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UniProt
- Q9Y2K6
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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