RIN1 抗体 (C-Term)
Quick Overview for RIN1 抗体 (C-Term) (ABIN7465272)
抗原
See all RIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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交叉反应
 - 人
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纯化方法
 - Purified by antigen-affinity chromatography.
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免疫原
 - Recombinant protein encompassing a sequence within the C-terminus region of human RIN1. The exact sequence is proprietary.
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亚型
 - IgG
 
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应用备注
 - WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , HeLa , HepG2
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1.67 mg/mL
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缓冲液
 - 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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- RIN1 (Ras and Rab Interactor 1 (RIN1))
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别名
 - Ras and Rab interactor 1
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背景
 - Ras and Rab interactor 1,Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
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分子量
 - 84 kDa
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基因ID
 - 9610
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UniProt
 - Q13671
 
抗原
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