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THOC7 抗体

This anti-THOC7 antibody is a 兔 多克隆 antibody detecting THOC7 in WB, ICC 和 IF. Suitable for 人.
产品编号 ABIN7465253
发货至: 中国

Quick Overview for THOC7 抗体 (ABIN7465253)

抗原

See all THOC7 抗体
THOC7 (THO Complex 7 (THOC7))

适用

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宿主

  • 22

克隆类型

  • 22
多克隆

标记

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This THOC7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human THOC7. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , Mouse brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    THOC7 (THO Complex 7 (THOC7))

    别名

    THO complex 7

    背景

    THO complex 7 , NIF3L1BP1 , fSAP24 , hTREX30,Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.

    分子量

    24 kDa

    基因ID

    80145

    UniProt

    Q6I9Y2
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