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UBXN1 抗体

This anti-UBXN1 antibody is a 兔 多克隆 antibody detecting UBXN1 in WB, IHC (p), ICC 和 IF. Suitable for 人.
产品编号 ABIN7465241
发货至: 中国
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Quick Overview for UBXN1 抗体 (ABIN7465241)

抗原

See all UBXN1 抗体
UBXN1 (UBX Domain Protein 1 (UBXN1))

适用

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宿主

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克隆类型

  • 32
多克隆

标记

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This UBXN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human UBXN1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , NIH-3T3 , JC , BCL-1

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.78 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    UBXN1 (UBX Domain Protein 1 (UBXN1))

    别名

    UBX domain protein 1

    背景

    UBX domain protein 1 , 2B28 , SAKS1 , UBXD10,Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol.

    分子量

    33 kDa

    基因ID

    51035

    UniProt

    Q04323
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