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VASP 抗体 (C-Term)

The 兔 多克隆 anti-VASP antibody (ABIN7465226) specifically detects VASP in WB, IF, IHC (p) 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7465226
发货至: 中国
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Quick Overview for VASP 抗体 (C-Term) (ABIN7465226)

抗原

See all VASP 抗体
VASP (Vasodilator-Stimulated phosphoprotein (VASP))

适用

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宿主

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克隆类型

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多克隆

标记

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This VASP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
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    C-Term

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human VASP. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , Neuro2A , C8D30 , Raw264.7 , C2C12 , Rat-2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.96 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    VASP (Vasodilator-Stimulated phosphoprotein (VASP))

    别名

    vasodilator stimulated phosphoprotein

    背景

    Vasodilator stimulated phosphoprotein,Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq]

    分子量

    40 kDa

    基因ID

    7408

    UniProt

    P50552

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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