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PUF60 抗体

This anti-PUF60 antibody is a 小鼠 单克隆 antibody detecting PUF60 in WB, IHC (p), IF 和 ICC. Suitable for 人.
产品编号 ABIN7465218
发货至: 中国

Quick Overview for PUF60 抗体 (ABIN7465218)

抗原

See all PUF60 抗体
PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

适用

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宿主

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小鼠

克隆类型

  • 64
  • 5
单克隆

标记

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This PUF60 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

GT677
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Affinity purified by Protein G.

    免疫原

    The immunogen used to generate this antibody corresponds to human PUF60

    亚型

    IgG2a
  • 应用备注

    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , mouse brain , rat brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

    别名

    poly(U) binding splicing factor 60

    背景

    Poly(U) binding splicing factor 60 , FIR , RoBPI , SIAHBP1 , VRJS,The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq]

    分子量

    60 kDa

    基因ID

    22827

    UniProt

    Q9UHX1
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