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MIP 抗体 (PE)

This PE-conjugated 兔 多克隆 anti-MIP antibody specifically detects MIP in IF (p). The antibody is reactive with 人, 小鼠, 大鼠, 豚鼠, Pig, 小鸡 和 Cow samples.
产品编号 ABIN719586
发货至: 中国
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Quick Overview for MIP 抗体 (PE) (ABIN719586)

抗原

See all MIP 抗体
MIP (Major Intrinsic Protein of Lens Fiber (MIP))

适用

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人, 小鼠, 大鼠, 豚鼠, Pig, 小鸡, Cow

宿主

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克隆类型

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多克隆

标记

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This MIP antibody is conjugated to PE

应用范围

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Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 特异性

    Excitation / Emission Wavelengths: 565nm/578nm

    交叉反应

    大鼠, 小鸡, 猪, 牛, 豚鼠

    纯化方法

    purified by Protein A

    免疫原

    KLH conjugated synthetic peptide derived from human AQP0

    亚型

    IgG
  • 说明

    Excitation / Emission wavelength: 496nm / 578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 µg/µL

    缓冲液

    Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 4 °C for 12 months

    有效期

    12 months
  • 抗原

    MIP (Major Intrinsic Protein of Lens Fiber (MIP))

    别名

    AQP0

    背景

    Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporins. Aquaporin 0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 has been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80% of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal recessive congenital cataract. The lens opacity mutation (LOP) is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains. The N and C terminus are predicted to be cytoplasmic.

    分子量

    28kDa

    基因ID

    4284
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