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PC 抗体 (C-Term)

This anti-PC antibody is a 兔 多克隆 antibody detecting PC in WB, IP, ICC, IHC (p), IF 和 RIP. Suitable for 人.
产品编号 ABIN7465195
发货至: 中国

Quick Overview for PC 抗体 (C-Term) (ABIN7465195)

抗原

See all PC 抗体
PC (Pyruvate Carboxylase (PC))

适用

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宿主

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克隆类型

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多克隆

标记

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This PC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), RNA-Binding Protein Immunoprecipitation (RIP)
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    C-Term

    交叉反应

    人, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human Pyruvate Carboxylase. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:857. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.69 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PC (Pyruvate Carboxylase (PC))

    别名

    pyruvate carboxylase

    背景

    Pyruvate carboxylase , PCB,This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq]

    分子量

    130 kDa

    基因ID

    5091

    UniProt

    P11498
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