CCAR1 抗体
Quick Overview for CCAR1 抗体 (ABIN7465120)
抗原
See all CCAR1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CCAR1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (AA 1-200) antibody
CCAR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) antibodyCCAR1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (AA 1-200) antibodyCCAR1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (Internal Region) antibodyVerified CCAR1 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) antibodyCCAR1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
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别名
- cell division cycle and apoptosis regulator 1
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背景
- Cell division cycle and apoptosis regulator 1,Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.
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分子量
- 133 kDa
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基因ID
- 55749
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UniProt
- Q8IX12
抗原
-
