THO Complex 5 抗体
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- 抗原 See all THO Complex 5 (THOC5) 抗体
- THO Complex 5 (THOC5)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This THO Complex 5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human THOC5. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product THOC5 Primary Antibody
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anti-THO Complex 5 (THOC5) (AA 2-53) antibody
THOC5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 5 (THOC5) (Internal Region) antibodyTHOC5 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 5 (THOC5) (AA 150-370) antibodyTHOC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T , A431 , HeLa
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.6 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- THO Complex 5 (THOC5)
- 别名
- THO complex 5 (THOC5 产品)
- 别名
- C22orf19 antibody, Fmip antibody, PK1.3 antibody, fSAP79 antibody, 1700060C24Rik antibody, A430085L24Rik antibody, Sgk2 antibody, fc54b09 antibody, wu:fc54b09 antibody, zgc:56190 antibody, zgc:76912 antibody, THOC5 antibody, fmip antibody, thoc5 antibody, thoc5-a antibody, thoc5-b antibody, THO complex 5 antibody, THO complex 5 S homeolog antibody, THO complex 5 L homeolog antibody, THOC5 antibody, Thoc5 antibody, thoc5 antibody, thoc5.S antibody, thoc5.L antibody
- 背景
- THO complex 5 , C22orf19 , Fmip , PK1.3 , fSAP79,Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction beteen KSHV ORF57 protein and THOC4. UAP56 functions as a bridge between THOC4 and the THO complex. THOC5 in conjunction with THOC4 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA. May be involved in the differentiation of granulocytes and adipocytes.
- 分子量
- 79 kDa
- 基因ID
- 8563
- UniProt
- Q13769
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