Emerin 抗体 (AA 25-125) (Biotin)
Quick Overview for Emerin 抗体 (AA 25-125) (Biotin) (ABIN719563)
抗原
See all Emerin (EMD) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 25-125
-
预测反应
- Human,Mouse,Rat,Dog,Cow,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human Emerin
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- Emerin (EMD)
-
别名
- Emerin
-
背景
-
Synonyms: EDMD, EMD, EMD_HUMAN, Emerin, Emery Dreuss muscular dystrophy, STA.
Background: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.Tissue specificity, Skeletal muscle, heart, colon, testis, ovary and pancreas.
-
基因ID
- 2010
抗原
-