ETV1 抗体
Quick Overview for ETV1 抗体 (ABIN7464928)
抗原
See all ETV1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody was rasied against ER81 isoform 1. Based on sequence homology, this antibody can recognize most ER81 isoforms, but it may be unable to recognize isoform 4 according to the customer's feedback.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ER81. The exact sequence is proprietary.
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亚型
- IgG
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anti-Ets Variant 1 (ETV1) (AA 148-257) antibody
ETV1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-Ets Variant 1 (ETV1) (AA 80-300) antibodyETV1 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 1 (ETV1) (AA 1-191) antibodyETV1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C8B6 unconjugated
anti-Ets Variant 1 (ETV1) (Middle Region) antibodyETV1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 1 (ETV1) (N-Term) antibodyETV1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 1 (ETV1) (Internal Region) antibodyVerified ETV1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ets Variant 1 (ETV1) (N-Term) antibodyETV1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 1 (ETV1) (C-Term) antibodyETV1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Bat, Hamster, 猴, Pig, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 1 (ETV1) (N-Term) antibodyETV1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 1 (ETV1) (AA 69-118) antibodyETV1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Rat2
Validation: Orthogonal, Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.83 mg/mL
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缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ETV1 (Ets Variant 1 (ETV1))
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别名
- ETS variant 1
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背景
- ETS variant 1 , ER81,This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2016]
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分子量
- 55 kDa
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基因ID
- 2115
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UniProt
- P50549
抗原
-
