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PDGFRB 抗体 (pTyr751)

This 兔 多克隆 anti-PDGFRB antibody specifically detects PDGFRB in WB, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7464880
发货至: 中国
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Quick Overview for PDGFRB 抗体 (pTyr751) (ABIN7464880)

抗原

See all PDGFRB 抗体
PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

适用

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宿主

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克隆类型

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多克隆

标记

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This PDGFRB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    pTyr751

    交叉反应

    小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide surrounding phospho Tyr751 of human PDGF Receptor beta. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: PDGF treated NIH-3T3

    Validation: Comparison, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.12 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

    别名

    platelet derived growth factor receptor beta

    背景

    Platelet derived growth factor receptor beta , CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR-1 , PDGFR1 , PENTT,This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]

    分子量

    124 kDa

    基因ID

    5159

    UniProt

    P09619

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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