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IRF4 抗体

This anti-IRF4 antibody is a 兔 多克隆 antibody detecting IRF4 in WB 和 IP. Suitable for 人.
产品编号 ABIN7464818
发货至: 中国

Quick Overview for IRF4 抗体 (ABIN7464818)

抗原

See all IRF4 抗体
IRF4 (Interferon Regulatory Factor 4 (IRF4))

适用

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宿主

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克隆类型

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多克隆

标记

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This IRF4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human IRF4 / MUM1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: NCI-H929

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    IRF4 (Interferon Regulatory Factor 4 (IRF4))

    别名

    interferon regulatory factor 4

    背景

    Interferon regulatory factor 4 , LSIRF , MUM1 , NF-EM5 , SHEP8,The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

    分子量

    52 kDa

    基因ID

    3662

    UniProt

    Q15306

    途径

    Chromatin Binding
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