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Rhotekin 抗体 (N-Term)

This anti-Rhotekin antibody is a 兔 多克隆 antibody detecting Rhotekin in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7464752
发货至: 中国

Quick Overview for Rhotekin 抗体 (N-Term) (ABIN7464752)

抗原

See all Rhotekin (RTKN) 抗体
Rhotekin (RTKN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Rhotekin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    N-Term

    交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human Rhotekin. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , Jurkat , Raji , NCI-H929 , human Rhotekin-transfected 293T cells

    Validation: Overexpression

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.54 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Rhotekin (RTKN)

    别名

    rhotekin

    背景

    Rhotekin,This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

    分子量

    63 kDa

    基因ID

    6242

    UniProt

    Q9BST9
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