SOX2 抗体
Quick Overview for SOX2 抗体 (ABIN7464615)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
- 
    
- 
                                            
交叉反应
 - 人, 小鼠, 大鼠, 斑马鱼
 - 
                                            
纯化方法
 - Affinity purified by Protein G.
 - 
                                            
免疫原
 - Recombinant protein encompassing a sequence within the center region of human SOX2. The exact sequence is proprietary.
 - 
                                            
亚型
 - IgG1
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - WB: 1:500-1:10000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
 - 
                                            
说明
 - 
                        
Positive Control: human ESC , zebrafish eye , NT2D1 , PC-3 , U87-MG , SK-N-SH
Validation: Comparison, KO/KD
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
状态
 - Liquid
 - 
                                            
浓度
 - 1 mg/mL
 - 
                                            
缓冲液
 - PBS, No Preservative
 - 
                                            
储存液
 - Without preservative
 - 
                                            
储存条件
 - 4 °C,-20 °C
 - 
                                            
储存方法
 - Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
 - 
                                            
 - 
    
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
 - 
                                            
别名
 - SRY-box 2
 - 
                                            
背景
 - SRY-box 2 , ANOP3 , MCOPS3,This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
 - 
                                            
分子量
 - 34 kDa
 - 
                                            
基因ID
 - 6657
 - 
                                            
UniProt
 - P48431
 - 
                                            
途径
 - Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
 
抗原
 -