CHD1L 抗体
Quick Overview for CHD1L 抗体 (ABIN7464584)
抗原
See all CHD1L 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CHD1L. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:1000-1:10000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2 nucleus , 293T
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.02 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))
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别名
- chromodomain helicase DNA binding protein 1 like
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背景
- Chromodomain helicase DNA binding protein 1 like , ALC1 , CHDL,In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM]
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分子量
- 101 kDa
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基因ID
- 9557
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UniProt
- Q86WJ1
抗原
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