NCOR1 抗体 (C-Term)
Quick Overview for NCOR1 抗体 (C-Term) (ABIN7464507)
抗原
See all NCOR1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            交叉反应
- 人
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                                            纯化方法
- Purified by antigen-affinity chromatography.
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                                            免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NCOR1. The exact sequence is proprietary.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            说明
- 
                        Positive Control: HeLa nuclear extract Validation: Orthogonal 
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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    - NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
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                                            别名
- nuclear receptor corepressor 1
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                                            背景
- Nuclear receptor corepressor 1 , N-CoR , N-CoR1 , PPP1R109 , TRAC1 , hN-CoR,This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. [provided by RefSeq]
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                                            分子量
- 270 kDa
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                                            基因ID
- 9611
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                                            UniProt
- O75376
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                                            途径
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
 抗原
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