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REST 抗体 (C-Term)

This anti-REST antibody is a 兔 多克隆 antibody detecting REST in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7464503
发货至: 中国

Quick Overview for REST 抗体 (C-Term) (ABIN7464503)

抗原

See all REST 抗体
REST (RE1-Silencing Transcription Factor (REST))

适用

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宿主

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克隆类型

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多克隆

标记

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This REST antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human REST. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HeLa nuclear , U87-MG nuclear extract , HeLa

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    REST (RE1-Silencing Transcription Factor (REST))

    别名

    RE1 silencing transcription factor

    背景

    RE1 silencing transcription factor , DFNA27 , GINGF5 , HGF5 , NRSF , WT6 , XBR,This gene encodes a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described, however, their full length nature has not been determined. [provided by RefSeq]

    分子量

    122 kDa

    基因ID

    5978

    UniProt

    Q13127

    途径

    Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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