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CA9 抗体 (N-Term)

This anti-CA9 antibody is a 小鼠 单克隆 antibody detecting CA9 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7464487
发货至: 中国

Quick Overview for CA9 抗体 (N-Term) (ABIN7464487)

抗原

See all CA9 抗体
CA9 (Carbonic Anhydrase IX (CA9))

适用

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宿主

  • 95
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小鼠

克隆类型

  • 69
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单克隆

标记

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This CA9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

GT14212
  • 抗原表位

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    N-Term

    交叉反应

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human Carbonic Anhydrase IX. The exact sequence is proprietary.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HeLa (200 μM CoCl2 treatment for 24 hr) , 30u g HeLa (200 μM CoCl2 treatment for 48 hr) , HeLa (1% O2 treatment for 24 hr) , HeLa (1% O2 treatment for 48 hr)

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CA9 (Carbonic Anhydrase IX (CA9))

    别名

    carbonic anhydrase 9

    背景

    Carbonic anhydrase 9 , CAIX , MN,Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq]

    分子量

    50 kDa

    基因ID

    768

    UniProt

    Q16790
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