ERN1 抗体 (pSer724)
Quick Overview for ERN1 抗体 (pSer724) (ABIN7464485)
抗原
See all ERN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer724
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide surrounding phospho Ser724 of human IRE1 alpha. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa (100 nM Calyculin A , 30 min)
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.18 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
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别名
- endoplasmic reticulum to nucleus signaling 1
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背景
- Endoplasmic reticulum to nucleus signaling 1 , IRE1 , IRE1P , IRE1a , hIRE1p,The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq]
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分子量
- 110 kDa
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基因ID
- 2081
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UniProt
- O75460
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途径
- ER-Nucleus Signaling, Unfolded Protein Response
抗原
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