MUL1 抗体
Quick Overview for MUL1 抗体 (ABIN7464298)
抗原
See all MUL1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- Drosophila melanogaster, 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human MUL1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , A431 membrane extract
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.88 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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别名
- mitochondrial E3 ubiquitin protein ligase 1
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背景
- Mitochondrial E3 ubiquitin protein ligase 1 , C1orf166 , GIDE , MAPL , MULAN , RNF218,E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
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分子量
- 40 kDa
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基因ID
- 79594
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UniProt
- Q969V5
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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