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E2F2 抗体 (N-Term)

This anti-E2F2 antibody is a 兔 多克隆 antibody detecting E2F2 in WB. Suitable for 人.
产品编号 ABIN7464263
发货至: 中国

Quick Overview for E2F2 抗体 (N-Term) (ABIN7464263)

抗原

See all E2F2 抗体
E2F2 (E2F Transcription Factor 2 (E2F2))

适用

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宿主

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克隆类型

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多克隆

标记

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This E2F2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human E2F2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T nuclear extract , K562 nuclear extract

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.93 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    E2F2 (E2F Transcription Factor 2 (E2F2))

    别名

    E2F transcription factor 2

    背景

    E2F transcription factor 2 , E2F-2,The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq]

    分子量

    48 kDa

    基因ID

    1870

    UniProt

    Q14209

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
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