RAB7A 抗体
Quick Overview for RAB7A 抗体 (ABIN7464167)
抗原
See all RAB7A 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human RAB7A. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: 293T , A431 , HeLa , HepG2
Validation: Comparison, KO/KD, Overexpression
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.36 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
-
别名
- RAB7A, member RAS oncogene family
-
背景
- RAB7A, member RAS oncogene family , PRO2706 , RAB7,RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
-
分子量
- 23 kDa
-
基因ID
- 7879
-
UniProt
- P51149
-
途径
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
抗原
-