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CD16 抗体

The 小鼠 单克隆 anti-CD16 antibody is suitable to detect CD16 in samples from 人. It has been validated for FACS 和 BR.
产品编号 ABIN7457995
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD16 抗体 (ABIN7457995)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Blocking Reagent (BR)

克隆位点

3G8
  • 纯化方法

    Purified

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Matching Isotype Control: Purified Mouse IgG1, κ Isotype Control[MOPC-21] (ABIN7469768)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    CD16

    别名

    CD16

    背景

    FcγRIII,Fc gamma receptor,Fc gamma receptor 3,CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

    基因ID

    941

    UniProt

    P08637, O75015

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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