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IL-5 抗体

This anti-IL-5 antibody is a 大鼠 单克隆 antibody detecting IL-5 in Neut, ICFC 和 Dep. Suitable for 人.
产品编号 ABIN7457979
发货至: 中国

Quick Overview for IL-5 抗体 (ABIN7457979)

抗原

See all IL-5 (IL5) 抗体
IL-5 (IL5) (Interleukin 5 (IL5))

适用

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宿主

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大鼠

克隆类型

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单克隆

标记

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This IL-5 antibody is un-conjugated

应用范围

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Neutralization (Neut), Intracellular Flow Cytometry (ICFC), Depletion (Dep)

克隆位点

TRFK5
  • 纯化方法

    Purified

    过滤

    0.2 μm filtered

    内毒素水平

    Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Matching Isotype Control: AF/LE Purified Rat IgG1, κ Isotype Control (ABIN7469818)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    IL-5 (IL5) (Interleukin 5 (IL5))

    别名

    IL-5

    背景

    Interleukin-5,IL-5,B-cell differentiation factor I,T-cell replacing factor,TRF,IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70 % identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

    基因ID

    3567, 16191

    UniProt

    P05113, P04401

    途径

    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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