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CD8 alpha 抗体

This anti-CD8 alpha antibody is a 大鼠 单克隆 antibody detecting CD8 alpha in FACS, BR 和 Dep. Suitable for 小鼠.
产品编号 ABIN7457930
发货至: 中国

Quick Overview for CD8 alpha 抗体 (ABIN7457930)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Blocking Reagent (BR), Depletion (Dep)

克隆位点

53-6-7
  • 纯化方法

    Purified

    过滤

    0.2 μm filtered

    内毒素水平

    Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Matching Isotype Control: AF/LE Purified Rat IgG2a, κ Isotype Control (ABIN7469836)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL,CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

    基因ID

    12525

    UniProt

    P01731

    途径

    TCR Signaling
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