CD86 抗体 (PE-Cy5)
Quick Overview for CD86 抗体 (PE-Cy5) (ABIN7457209)
抗原
See all CD86 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
-
说明
-
Matching Isotype Control: PE/Cyanine5 Mouse IgG1, κ Isotype Control
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.05 % Proclin300, 1 % BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
-
-
- CD86
-
别名
- CD86
-
背景
- T-lymphocyte activation antigen CD86,Cd86,Activation B7-2 antigen,Early T-cell costimulatory molecule 1,ETC-1,CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
-
基因ID
- 942
-
UniProt
- P42081
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
-