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CD47 抗体 (Biotin)

This anti-CD47 antibody is a 小鼠 单克隆 antibody detecting CD47 in FACS. Suitable for 人.
产品编号 ABIN7456647
发货至: 中国

Quick Overview for CD47 抗体 (Biotin) (ABIN7456647)

抗原

See all CD47 抗体
CD47

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD47 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

CC2C6D4
  • 亚型

    IgG1, kappa
  • 应用备注

    For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

    说明

    Matching Isotype Control: Biotin Mouse Rat IgG1, κ Isotype Control (ABIN7469769)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    CD47

    别名

    CD47

    背景

    Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP,CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47, in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.

    基因ID

    961

    UniProt

    Q08722
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