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Glypican 3 抗体

This 兔 Chimeric antibody specifically detects Glypican 3 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7490626
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Glypican 3 抗体 (ABIN7490626)

抗原

See all Glypican 3 (GPC3) 抗体
Glypican 3 (GPC3)

片段

Fc fragment

适用

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宿主

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克隆类型

  • 114
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Chimeric

标记

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This Glypican 3 antibody is un-conjugated

应用范围

  • 107
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Flow Cytometry (FACS)
  • 产品特性

    Rabbit/Human Fc chimeric IgG1

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt  1:100

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    Glypican 3 (GPC3)

    别名

    GPC3

    背景

    DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
    Description: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] References: Fu Ying,Urban Daniel J,Nani Roger R et al. Glypican-3-Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.[J] .Hepatology, 2019, 70: 563-576. Zhang Yi-Fan,Ho Mitchell,Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma.

    UniProt

    P51654

    途径

    Glycosaminoglycan Metabolic Process
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