SIRPA 抗体 (Biotin)
Quick Overview for SIRPA 抗体 (Biotin) (ABIN7490543)
抗原
See all SIRPA 抗体适用
宿主
克隆类型
标记
应用范围
- 
    
- 
                                            
产品特性
 - Rabbit IgG
 - 
                                            
纯化方法
 - Purified from cell culture supernatant by affinity chromatography
 - 
                                            
亚型
 - IgG
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - Flow Cyt 1:100, IP 1:30
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
状态
 - Lyophilized
 - 
                                            
储存条件
 - -20 °C,-80 °C
 - 
                                            
储存方法
 - Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
 - 
                                            
有效期
 - 12 months
 
 - 
                                            
 - 
    
- SIRPA (Signal-Regulatory Protein alpha (SIRPA))
 - 
                                            
别名
 - SIRPalpha
 - 
                                            
背景
 - 
                        BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2,
Description: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008] - 
                                            
UniProt
 - P78324
 
抗原
 -