CD47 抗体
Quick Overview for CD47 抗体 (ABIN7490508)
抗原
See all CD47 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Rabbit IgG
-
纯化方法
- Purified from cell culture supernatant by affinity chromatography
-
亚型
- IgG
-
-
-
-
应用备注
- ELISA 1:5000-10000, Flow Cyt 1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
有效期
- 12 months
-
-
- CD47
-
别名
- CD47
-
背景
-
CD47, MER6, IAP, OA3,
Description: Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. -
UniProt
- Q08722
抗原
-