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CD56 抗体

This anti-CD56 antibody is a 兔 单克隆 antibody detecting CD56 in FACS 和 ELISA. Suitable for 人.
产品编号 ABIN7490488
发货至: 中国

Quick Overview for CD56 抗体 (ABIN7490488)

抗原

See all CD56 (NCAM1) 抗体
CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

适用

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宿主

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克隆类型

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单克隆

标记

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This CD56 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA
  • 产品特性

    Rabbit IgG

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG
  • 应用备注

    ELISA 1:5000-10000, Flow Cyt  1:100

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

    别名

    CD56

    背景

    NCAM1, CD56, MSK39, NCAM,
    Description: This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. This protein is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. This protein plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and other components of the extracellular matrix and by triggering signalling cascades involving FYN-focal adhesion kinase (FAK), mitogen-activated protein kinase (MAPK), and phosphatidylinositol 3-kinase (PI3K). One prominent isoform of this gene, cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients whereas increased severity of COVID-19 is correlated with decreased abundance of CD56-expressing NK cells in peripheral blood. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.

    UniProt

    P13591
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