TNFSF8 抗体
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北京 101111
Quick Overview for TNFSF8 抗体 (ABIN7490486)
抗原
See all TNFSF8 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Rabbit IgG
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG
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应用备注
- ELISA 1:5000-10000, Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
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别名
- CD30 Ligand
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背景
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CD30-L,CD153,TNFSF8,CD30L,CD30LG,CD153 antigen,CD30 antigen ligand,CD30 Ligand,
Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30 lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. -
UniProt
- P32971
抗原
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