Progesterone Receptor 抗体
Quick Overview for Progesterone Receptor 抗体 (ABIN7455133)
抗原
See all Progesterone Receptor (PGR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti-Progesterone Receptor Monoclonal Antibody [188]
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免疫原
- recombinant human Progesterone Receptor
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亚型
- IgG
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应用备注
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 6 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Progesterone Receptor (PGR)
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别名
- Progesterone Receptor
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背景
- Background: The progesterone receptor (PR) is a member of the steroid receptor superfamily that binds progesterone and is critical to all aspects of reproductive development and the establishment and maintenance of pregnancy. When bound by progesterone, PR enters the nucleus to function in gene-specific transcriptional activation. Progesterone receptor expression is regulated by estrogen. Recent studies have found that the status of the progesterone receptor in breast tumors may be an indicator of how tumors will respond to tamoxifen treatment.
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基因ID
- 5241
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NCBI登录号
- NP_000917
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UniProt
- P06401
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
抗原
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