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Progesterone Receptor 抗体

This anti-Progesterone Receptor antibody is a 小鼠 单克隆 antibody detecting Progesterone Receptor in WB, IP, ICC, FACS 和 IHC (fp). Suitable for 人.
产品编号 ABIN7455133
发货至: 中国

Quick Overview for Progesterone Receptor 抗体 (ABIN7455133)

抗原

See all Progesterone Receptor (PGR) 抗体
Progesterone Receptor (PGR)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Progesterone Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

188
  • 原理

    Mouse anti-Progesterone Receptor Monoclonal Antibody [188]

    免疫原

    recombinant human Progesterone Receptor

    亚型

    IgG
  • 应用备注

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 6 μL/1 mg lysate

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 01:01,00

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Progesterone Receptor (PGR)

    别名

    Progesterone Receptor

    背景

    Background: The progesterone receptor (PR) is a member of the steroid receptor superfamily that binds progesterone and is critical to all aspects of reproductive development and the establishment and maintenance of pregnancy. When bound by progesterone, PR enters the nucleus to function in gene-specific transcriptional activation. Progesterone receptor expression is regulated by estrogen. Recent studies have found that the status of the progesterone receptor in breast tumors may be an indicator of how tumors will respond to tamoxifen treatment.

    基因ID

    5241

    NCBI登录号

    NP_000917

    UniProt

    P06401

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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