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Recombinant BCL6 抗体 (AA 375-425)

The 兔 单克隆 anti-BCL6 antibody is suitable to detect BCL6 in samples from 人. It has been validated for IHC, WB, FACS, IP 和 ICC.
产品编号 ABIN7455109
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant BCL6 抗体 (AA 375-425) (ABIN7455109)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This BCL6 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

BLR143H
  • 抗原表位

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    AA 375-425

    原理

    Rabbit anti-Bcl6 Recombinant Monoclonal Antibody [BLR143H]

    纯化方法

    Purified

    免疫原

    between AA 375 and 425

    亚型

    IgG
  • 应用备注

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 6 μL/1 mg lysate

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 01:01,00

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1000 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    Bcl6

    背景

    Bcl6 is a zinc finger transcription factor and contains an N-terminal POZ domain. It acts as a sequence-specific repressor of transcription and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. Bcl6 can interact with a variety of POZ-containing proteins that function as transcription corepressors. Bcl6 is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL) and may be involved in the pathogenesis of DLCL. [taken from NCBI Entrez Gene (Gene ID: 604)].

    基因ID

    604

    UniProt

    P41182

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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