MAVS 抗体 (AA 150-200)
Quick Overview for MAVS 抗体 (AA 150-200) (ABIN7455082)
抗原
See all MAVS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-200
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原理
- Rabbit anti-MAVS/VISA Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 150 and 200
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
ICC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE cell sections.
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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别名
- MAVS/VISA
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背景
- Background: Mitochondrial Antiviral-Signaling Protein (MAVS), also known as Virus-Induced Signaling Adaptor (VISA), is an adaptor protein that functions in the activation of the nuclear factor KappaB (NF-kappaB) and interferon regulatory factor 3 (IRF3) to mediate host innate immune responses against double-stranded RNA viral infection. MAVS (VISA) is localized to the outer mitochondrial membrane. Hepatitis C virus NS3/4A protease cleaves MAVS as part of an immune-evasion strategy.
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基因ID
- 57506
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UniProt
- Q7Z434
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途径
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
抗原
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