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RAN 抗体 (AA 166-216)

Name: RAN 抗体 (AA 166-216)
Brand: antibodies-online
SKU: ABIN7455018
Availability: OutOfStock

This anti-RAN antibody is a 兔多克隆 antibody detecting RAN in WB, IP 和 IHC (fp). Suitable for 人和小鼠.

产品编号 ABIN7455018

发货至: 中国

Quick Overview for RAN 抗体 (AA 166-216) (ABIN7455018)

抗原

See all RAN 抗体

RAN (RAN, Member RAS Oncogene Family (RAN))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This RAN antibody is un-conjugated

应用范围

Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Discover our top product RAN Primary Antibody

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AA 166-216

原理

Rabbit anti-RAN Antibody, Affinity Purified

预测反应

Rat,Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Dog,Orangutan

纯化方法

Affinity Purified

免疫原

Between AA 166 and 216

亚型

IgG
anti-RAN, Member RAS Oncogene Family (RAN) (AA 1-216) antibody
RAN 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8D1A6 unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (N-Term) antibody
Verified RAN 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 2-216) antibody
RAN 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 12-39) antibody
RAN 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 1-179) antibody
RAN 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 1-216) antibody
RAN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 12-39), (N-Term) antibody
RAN 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20229 unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 112-140) antibody
RAN 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 197-210) antibody
Verified RAN 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 1-216) antibody
RAN 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000

限制

仅限研究用
浓度

1000 μg/mL

缓冲液

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

有效期

12 months
抗原

RAN (RAN, Member RAS Oncogene Family (RAN))

别名

RAN

背景

Background: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor [taken from NCBI Entrez Gene (Gene ID: 5901)].

基因ID

5901

NCBI登录号

NP_006316

UniProt

P62826

途径

Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus