FNTA 抗体 (AA 329-379)
Quick Overview for FNTA 抗体 (AA 329-379) (ABIN7455017)
抗原
See all FNTA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 329-379
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原理
- Rabbit anti-FNTA Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 329 and 379
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
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别名
- FNTA
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背景
- Background: Farnesyl-protein transferase alpha-subunit (FNTA) catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity) [taken from the Universal Protein Resource (UniProt) P49354].
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基因ID
- 2339
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NCBI登录号
- NP_002018
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UniProt
- P49354
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途径
- Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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