Caldesmon 抗体 (AA 743-793)
Quick Overview for Caldesmon 抗体 (AA 743-793) (ABIN7455009)
抗原
See all Caldesmon (CALD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 743-793
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原理
 - Rabbit anti-Caldesmon Antibody, Affinity Purified
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预测反应
 - Rat
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纯化方法
 - Affinity Purified
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免疫原
 - Between AA 743 and 793
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亚型
 - IgG
 
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
 - 仅限研究用
 
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浓度
 - 1000 μg/mL
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缓冲液
 - Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C
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有效期
 - 12 months
 
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
 - Caldesmon
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背景
 - Background: Caldesmon is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of caldesmon possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction [taken from NCBI Entrez Gene (Gene ID: 800)].
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基因ID
 - 800
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NCBI登录号
 - NP_149129
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UniProt
 - Q05682
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途径
 - Myometrial Relaxation and Contraction
 
抗原
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